Clinicopathological Profiles and Prognosis of Postoperative HER2-Mutant Non-Small Cell Lung Cancer: A Real-World Analysis.

Overall, 76.6% of patients exhibited invasive adenocarcinoma phenotypes.

Histopathological examination revealed highly invasive papillary and micropapillary components in 51.9% and 45.5% of patients, respectively.

However, PD-L1 expression status, TP53 alterations, and histological phenotypes demonstrated no significant impact on DFS.

Among the entire cohort, 80.5% of patients experienced postoperative recurrence, with the lung being the most frequent site of metastasis.