Enhanced Pain Management With Combined EMLA Patch and Local Anesthetic Infiltration in Transradial…

Cohort studyClinical cardiology· Aug 2026

Enhanced Pain Management With Combined EMLA Patch and Local Anesthetic Infiltration in Transradial Angiography.

Mohamad Amer Nashtar, Obayda Azizy, Jörn Trippe … Martin Steinmetz

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Regional AnesthesiaCohort studyTreatmentQ2IF 2.6

Combined EMLA patch plus lidocaine infiltration cut pain in transradial angiography

Enhanced Pain Management With Combined EMLA Patch and Local Anesthetic Infiltration in Transradial Angiography.

Mohamad Amer Nashtar … Martin Steinmetz

Clinical cardiology · Aug 2026 · Q2 in General Medicine

Background

Pain at the radial access site remains common during coronary angiography.

Purpose

This study compared the analgesic effectiveness of three strategies: EMLA patch, local lidocaine infiltration, and their combination.

Methods

In this retrospective study, 275 patients undergoing elective transradial coronary angiography received either EMLA patch (n = 88), local infiltration (n = 96), or combined EMLA + infiltration (n = 91).

n = 275 patients

Results

combined EMLA plus lidocaine gave near-zero pain, less than either alone

0NPRS s

Combined

1NPRS s

EMLA

3NPRS s

Infiltration

More results

Similar findings were observed for the 24 h cumulative pain score.

An EMLA application time of 100-300 min was associated with substantially lower pain than shorter or longer durations (both p < 0.001).

Obesity (BMI ≥ 30 kg/m 2 ) independently predicted higher procedural pain (B = 0.96; p = 0.020) and higher 24 h cumulative pain (B = 2.70; p = 0.002).

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Conclusion · 1 of 2

Combined EMLA patch plus local lidocaine infiltration was associated with superior analgesia during and after transradial coronary angiography compared with either method alone.

Conclusion · 2 of 2

An EMLA application time of 100-300 min may optimize analgesic effectiveness, while patients with obesity may benefit from tailored pain-management strategies.

Enhanced Pain Management With Combined EMLA Patch and Local Anesthetic Infiltration in Transradial Angiography.

Enhanced Pain Management With Combined EMLA Patch and Local Anesthetic Infiltration in Transradial Angiography.

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