Transversus Abdominis Plane Block with Liposomal Bupivacaine versus Ropivacaine for Postoperative Cesarean…

Randomized trialDrug design, development and therapy· 2026

Transversus Abdominis Plane Block with Liposomal Bupivacaine versus Ropivacaine for Postoperative Cesarean Analgesia: A Randomized Controlled Trial.

Bomin Xing, Jiahui Lu, Chengtai Wang … Fangfang Han

Obstetric AnesthesiaRandomized trialQ1IF 6.0

Liposomal bupivacaine transversus abdominis plane block linked to fewer adverse events after cesarean delivery

Transversus Abdominis Plane Block with Liposomal Bupivacaine versus Ropivacaine for Postoperative Cesarean Analgesia: A Randomized Controlled Trial.

Bomin Xing … Fangfang Han

Drug design, development and therapy · 2026

Background

Effective postoperative analgesia is critical for enhanced recovery after cesarean delivery (cesarean delivery).

Methods

Were randomly assigned in a 1:1 fashion to either receive bilateral transversus abdominis plane blocks with liposomal bupivacaine 266 mg or with ropivacaine (ropivacaine) 150 mg.

n = 82 patients

Results

fewer complications overall with liposomal bupivacaine than ropivacaine

4.9%

LB

19.5%

RP

More results

A total of 82 patients participated in the study.

There was no significant between-group difference in movement visual analog scale scores at 24 hours.

However, movement visual analog scale scores were significantly lower in the liposomal bupivacaine group at 48 and 72 hours ( P <0.05).

More results

Additionally, the cumulative opioid usage over 72 hours was significantly decreased in the liposomal bupivacaine group ( P = 0.008).

“

Conclusion · 1 of 2

In this randomized controlled trial, liposomal bupivacaine did not significantly reduce pain scores at the predefined 24-hour primary endpoint compared with ropivacaine.

Conclusion · 2 of 2

Lower movement pain scores at 48 and 72 hours and a modest reduction in postoperative opioids consumption were observed as secondary findings.

Transversus Abdominis Plane Block with Liposomal Bupivacaine versus Ropivacaine for Postoperative Cesarean Analgesia: A Randomized Controlled Trial.

Transversus Abdominis Plane Block with Liposomal Bupivacaine versus Ropivacaine for Postoperative Cesarean Analgesia: A Randomized Controlled Trial.

Related papers