Nosological reappraisal of primary cutaneous apocrine carcinoma based on a clinicopathological and genetic analysis of 30 cases.

Male predominance (28/30, 93%), predominance in elderly patients (median age, 72 years; range, 33-89 years) and the favourite site of the axilla (29/30, 97%) were observed.

Histopathologically, all tumours harboured cytoplasmic zymogen-like granules; however, some (8/30, 27%) lacked apocrine secretion features.

Nucleoli were either moderately prominent (n = 17) or prominent (n = 13).

Apocrine gland hyperplasia was identified in 5 (17%) of the 30 cases.