Inflammatory features in placentas of women with endometriosis and their relation to maternal and neonatal… | ScholarDeck

Paper

Inflammatory features in placentas of women with endometriosis and their relation to maternal and neonatal outcomes.

New research · Pathology

Placenta · 1mo

Cohort studyPlacenta· Jun 2025

Inflammatory features in placentas of women with endometriosis and their relation to maternal and neonatal outcomes.

Liat Mor, Roni Goldenberg, Ran Keidar … Elad Barber

Read paper

Breast & Gynecologic PathologyCohort studyQ1IF 3.1

Endometriosis linked to higher rate of composite adverse neonatal outcomes.

Inflammatory features in placentas of women with endometriosis and their relation to maternal and neonatal outcomes.

Liat Mor … Elad Barber

Placenta · Jun 2025

Background

Its association with immune dysregulation and potential role in pregnancy complications remain unclear.

Purpose

This study examines the relationship between endometriosis and placental pathology to explore mechanisms underlying adverse pregnancy outcomes.

Methods

A retrospective cohort study included patients with endometriosis (n = 50) and a matched control group without endometriosis (n = 150) who delivered singleton term pregnancies at a tertiary center (2008-2023).

n = 50

Results

newborns had worse composite outcomes when mothers had endometriosis

16%

Endometriosis

Control

More results

Multivariable regression confirmed associations between endometriosis, inflammatory placental features, and adverse neonatal outcomes.

“

Conclusion · 1 of 2

Endometriosis is linked to increased placental inflammatory features and higher adverse neonatal outcome rates.

Conclusion · 2 of 2

These findings highlight the need for enhanced surveillance and targeted interventions in pregnancies complicated by endometriosis.

Read paper

0 comments

No comments yet. Be the first.

ScholarDeck.

Join the discussion on this paper

Create your profile

Related papers

Latest Foundational

Cohort Study

17.0 months

Median disease-free survival after surgery in 77 patients; 95% CI, 11.4-22.5 months.

Cohort Study

0.98

after adjustment, adjuvant chemotherapy showed no recurrence-free survival benefit; the hazard ratio sits near no effect

Study

All 3

every patient in the series relapsed, though two stabilized on TRK inhibitor therapy

Study

19 of the 20

nearly all comparator BRAF-mutated melanomas carried extra pathogenic mutations or copy number changes, which the nevi l

Cohort Study

22.5%

Share of methylation-profiled cases whose subgroup differed from the immunohistochemistry classification; all were initially called SHH-activated.

Study

12 of 16

Patients with confirmed adult-onset Still's disease whose skin biopsies showed dyskeratotic or necrotic keratinocytes in the upper epidermis.

Study

0.917

microvessel density separates carcinoma from adenoma well; 1.0 would be perfect discrimination

Cohort Study

16.873

Odds ratio: patients with loss of polarity had higher odds of neoplastic pathology on follow-up histology.