Short-term effects and attributable burden of ambient volatile organic compound mixtures on pediatric atopic dermatitis and asthma in Seoul.

Generalized additive models showed broadly consistent single-compound associations.

Estimated ecological Population Attributable Fractions under the 25th-percentile scenario were 7.0% for atopic dermatitis (G4) and 4.7% (G1), 4.0% (G2), and 6.5% (G4) for asthma.

IMPACT: This study quantifies the short-term effects of ambient volatile organic compounds mixtures on pediatric atopic dermatitis and asthma using advanced mixture models.

The findings suggest that aromatic volatile organic compounds, particularly toluene, were consistently associated with the observed health outcomes.