Food-induced anaphylaxis to plant allergens in adolescents and adults: Data from the allergy Vigilance Network (2002-2024).

Eleven allergens (wheat, peanut, buckwheat, soy, hazelnut, sesame, lupin, cashew, pine nut, walnut and almond) accounted for 85% of all plant-based diets-related food-induced anaphylaxis.

Wheat was the main elicitor in adults (26.9% adults vs 7.6% adolescents; P < 0.001).

Soy cases in adults were frequently associated with birch pollen allergy (18.8% adolescents vs 64.5% adults; P = 0.005), whereas soy-related food-induced anaphylaxis cases in adolescents occurred in the context of a prior legume-allergy diagnosis (50% adolescents vs 5.6% adults; P < 0.001).