Diagnostic accuracy of the Yokohama system for reporting breast fine-needle aspiration cytology and breast…

StudyCytoJournal· 2026

Diagnostic accuracy of the Yokohama system for reporting breast fine-needle aspiration cytology and breast imaging-reporting and data system in breast lesions.

Shakthivel V, Sana Ahuja, Sufian Zaheer … Chintamani Chintamani

CytopathologyStudyDiagnosisQ2IF 1.7

Yokohama Scenario B gave the highest diagnostic accuracy for breast lesion cytology

Diagnostic accuracy of the Yokohama system for reporting breast fine-needle aspiration cytology and breast imaging-reporting and data system in breast lesions.

Shakthivel V … Chintamani Chintamani

CytoJournal · 2026 · Q2 in Pathology

Background

The Yokohama system standardizes fine-needle aspiration cytology (fine-needle aspiration cytology) reporting for breast lesions, while the breast imaging-reporting and data system (BI-RADS) categorizes lesions based on imaging risk assessment.

Purpose

This study aimed to evaluate the diagnostic accuracy of fine-needle aspiration cytology using the Yokohama System in correlation with BI-RADS classifications.

Methods

A retrospective analysis was conducted on 188 breast lesion cases that underwent fine-needle aspiration cytology and were categorized using the BI-RADS system.

n = 188 breast lesion cases

87.7%

Results

87.7%

Scenario B correctly classified lesions as benign or malignant most often overall

n = 188 breast lesion cases

More results

Higher Yokohama and BI-RADS categories were more prevalent among malignant cases, with 64.9% in Yokohama category 5 and 51.9% in BI-RADS 5.

Sensitivity was highest in Yokohama Scenario C (81.8%), while specificity (96.4%) and positive predictive value (92.6%) were highest in Scenario A.

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Conclusion · 1 of 2

Fine-needle aspiration cytology using the Yokohama System and imaging-based BI-RADS classification both show high diagnostic accuracy for breast lesions.

Conclusion · 2 of 2

While their individual performance is comparable, further studies are needed to explore whether combining these modalities improves diagnostic outcomes in clinically indeterminate cases.

Diagnostic accuracy of the Yokohama system for reporting breast fine-needle aspiration cytology and breast imaging-reporting and data system in breast lesions.

Diagnostic accuracy of the Yokohama system for reporting breast fine-needle aspiration cytology and breast imaging-reporting and data system in breast lesions.

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