Microneedles for allergy skin testing: Comprehensive analysis of agreement, accuracy, and pain.

Median [interquartile range] Dp mean wheal diameters was smaller with microneedle (2 [0-8.13] mm) than lancet (4 [0-12.5 mm], P < .001).

For net Dp mean wheal diameters, Bland-Altman analysis indicated a mean bias of -2.1 mm for microneedle, with 93.3% within the limits of agreement.

At a 3 mm cutoff, sensitivity was 82.5%, specificity 94.3%, and accuracy 86%.

Median pain scores were significantly lower for microneedle (2.5 [0-9]) compared to lancet (8.0 [1-26], P < .001).