Prevalence of West Nile Virus in Children Being Evaluated for Lyme Disease. | ScholarDeck

Paper

Prevalence of West Nile Virus in Children Being Evaluated for Lyme Disease.

New research · Pediatrics

Vector borne and zoonotic diseases (Larchmont, N.Y.) · 2w

Case-controlVector borne and zoonotic diseases (Larchmont, N.Y.)· Aug 2026

Prevalence of West Nile Virus in Children Being Evaluated for Lyme Disease.

Christopher J Woll, Stephanie Hadley, Amy B Dean … for Pedi Lyme Net

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Pediatric Infection & VaccinationCase-controlDiagnosisQ2IF 2.0

Active West Nile virus infection was rare in children evaluated for Lyme disease.

Prevalence of West Nile Virus in Children Being Evaluated for Lyme Disease.

Christopher J Woll … for Pedi Lyme Net

Vector borne and zoonotic diseases (Larchmont, N.Y.) · Aug 2026

Background

West Nile virus (West Nile virus) is a flavivirus typically transmitted between mosquitoes and birds with occasional spill-over into other animals, including humans.

Methods

We performed a nested case-control study within a prospective cohort study of children with suspected Lyme disease aged 1-21 years enrolled at 1 of 8 Pedi Lyme Net emergency departments.

n = 305

Results

0.3%

active infection was almost never found in this group

n = 305

More results

Of the 600 included patients, 15 (2.5%) had a positive and 53 (8.8%) had an equivocal West Nile virus MIA result.

Of these, only 1 had a positive EIA result.

Another child had a positive West Nile virus PCR test.

“

Conclusion

Acute West Nile virus infection is uncommon in pediatric patients being evaluated for suspected Lyme disease. Routine West Nile virus testing is not indicated when evaluating for suspected Lyme disease.

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