CT-Guided Lung Biopsy Using Dual-Energy Iodine Mapping to Target Lung Masses with Necrotic Tissue-A Proof-of-Concept Study.

Diagnostic yield was 9/11 (81.8%) for pulmonary lesions and 9/9 (100%) for mediastinal/pleural lesions.

Diagnoses included non-small-cell lung cancer (n = 8), Hodgkin lymphoma (n = 4), thymoma (n = 3), and other malignancies (n = 3).

Biopsy material was sufficient for additional molecular testing in 13/20 cases (65%).

Complications were minor (one pneumothorax not requiring drainage and two self-limited bleeding events).