Multiparametric MRI findings, PI-RADS scores, and gleason scores in prostate cancer patients at Kumasi…

Cross-sectionalBMC medical imaging· May 2026

Multiparametric MRI findings, PI-RADS scores, and gleason scores in prostate cancer patients at Kumasi, Ghana: a cross-sectional analysis.

Brenda Abena Ampah, Augustina Badu-Peprah, Adu Tutu Amankwa … Frank Quarshie

Genitourinary PathologyCross-sectionalDiagnosisQ1IF 4.4

Lower apparent diffusion coefficient values on mpMRI associated with higher-grade prostate cancer

Multiparametric MRI findings, PI-RADS scores, and gleason scores in prostate cancer patients at Kumasi, Ghana: a cross-sectional analysis.

Brenda Abena Ampah … Frank Quarshie

BMC medical imaging · May 2026

Background

Prostate cancer is a major cause of cancer-related morbidity and mortality in men, affecting about 2.3 million individuals every five years globally.

Purpose

This study examined the relationship between mpMRI findings, PI-RADS scores, and Gleason scores in patients with prostate cancer.

Methods

In this cross-sectional study, 76 men with prostate cancer underwent mpMRI.

n = 76 men

Results

lower apparent diffusion coefficient readings track with more aggressive tumors

78%

Gleason 7

76%

Gleason 8

100%

Gleason 9

More results

A weak but statistically significant positive correlation was observed between PI-RADS and Gleason scores (r = 0.31, p = 0.007).

PI-RADS 5 was predominantly associated with Gleason scores 7, 8, and 9, with proportions of 78%, 76%, and 100%, respectively (p < 0.001).

More results

For high-grade disease (Gleason score > 7), PI-RADS 5 demonstrated high sensitivity (86.2%) but low specificity (27.7%), consistent with its strength in capturing aggressive tumors within a biopsy-confirmed cohort.

“

Conclusion · 1 of 3

Higher PI-RADS categories and lower apparent diffusion coefficient values were associated with increasing histopathological aggressiveness in this cohort of biopsy-proven prostate cancer patients.

Conclusion · 2 of 3

These findings support the potential role of mpMRI in disease stratification, but should be interpreted cautiously given the cancer-only study population and skewed PI-RADS distribution.

Conclusion · 3 of 3

Larger prospective studies are required to validate these findings in mixed-suspicion cohorts.

Multiparametric MRI findings, PI-RADS scores, and gleason scores in prostate cancer patients at Kumasi, Ghana: a cross-sectional analysis.

Multiparametric MRI findings, PI-RADS scores, and gleason scores in prostate cancer patients at Kumasi, Ghana: a cross-sectional analysis.

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