Association of Body Roundness Index, A Body Shape Index, and Cardiometabolic Indices With Gastric Intestinal Metaplasia Severity Assessed by OLGA Staging.
Higher Body Roundness Index strongly linked to more severe gastric intestinal metaplasia stage.
Association of Body Roundness Index, A Body Shape Index, and Cardiometabolic Indices With Gastric Intestinal Metaplasia Severity Assessed by OLGA Staging.
Gastric intestinal metaplasia (intestinal metaplasia) is a recognized precancerous lesion whose progression may be influenced by metabolic dysfunction.
This study aims to investigate the relationship between Body Roundness Index, ABSI, BMI, and cardiometabolic indices (triglyceride-glucose, triglyceride-glucose-BMI) with the severity of intestinal metaplasia, as measured by the Operative Link on Gastritis Assessment (OLGA) staging system.
This prospective cross-sectional study included 250 patients who underwent upper gastrointestinal endoscopy with gastric biopsy.
higher body roundness index tracks with more advanced precancerous stomach changes
Of 250 patients (average age: 53.6±18.9 y; 51.6% female), 154 (61.6%) were identified as intestinal metaplasia-positive.
All anthropometric and cardiometabolic indices were significantly elevated in intestinal metaplasia-positive individuals (P<0.001).
In multivariate analysis, adjusting for age, sex, and Helicobacter pylori status, Body Roundness Index (odds ratio=1.665, 95% CI: 1.281-2.164, P<0.001), triglyceride-glucose (odds ratio=3.823, 95% CI: 1.925-7.591, P<0.001), and their combination (Body Roundness Index: odds ratio=1.469; triglyceride-glucose: odds ratio=2.654) persisted as independent predictors of intestinal metaplasia (intestinal metaplasia) positivity.
Body Roundness Index and triglyceride-glucose index are independently associated with gastric intestinal metaplasia severity and demonstrate superior predictive performance compared with conventional BMI.
These noninvasive, easily calculable indices may serve as practical tools for identifying individuals at increased risk of gastric precancerous lesions in clinical practice.