Concordance Between a Mohs Micrographic Surgeon and Dermatopathologist on Margin Status for Melanoma In Situ…

StudyDermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]· May 2025

Concordance Between a Mohs Micrographic Surgeon and Dermatopathologist on Margin Status for Melanoma In Situ and the Role of Immunohistochemical Stains.

Arianna F Yanes, Amina Bougrine, Adriano Piris … Abigail Waldman

DermatopathologyStudyClinical practiceQ2IF 1.2

Mohs surgeon and dermatopathologist agreed on melanoma in situ margin status in 95% of cases.

Concordance Between a Mohs Micrographic Surgeon and Dermatopathologist on Margin Status for Melanoma In Situ and the Role of Immunohistochemical Stains.

Arianna F Yanes … Abigail Waldman

Dermatologic surgery · May 2025 · Q2 in General Medicine

Background

Few studies have examined the concordance between Mohs surgeons and dermatopathologists' interpretation of margin status during Mohs micrographic surgery (mohs micrographic surgery) for melanoma in situ (MIS).

Purpose

The objectives of this study were to determine the concordance between a Mohs surgeon and dermatopathologist on margin status for MIS and to analyze the role of immunohistochemical stains during Mohs surgery.

Methods

This was a prospective study at 1 academic center of patients undergoing Mohs surgery for MIS.

95%

Results

95%

surgeon and pathologist agreed on clear vs positive margins in nearly all cases

More results

The dermatopathologist found H&E alone to be the most useful stain for the first stage of mohs micrographic surgery, while the Mohs surgeon found the combination of H&E and SOX10 most useful.

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Conclusion

There was a high concordance between the Mohs surgeon and dermatopathologist on MIS margin status. Immunohistochemical stains were more useful for the Mohs surgeon.

Concordance Between a Mohs Micrographic Surgeon and Dermatopathologist on Margin Status for Melanoma In Situ and the Role of Immunohistochemical Stains.

Concordance Between a Mohs Micrographic Surgeon and Dermatopathologist on Margin Status for Melanoma In Situ and the Role of Immunohistochemical Stains.

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