Estimated End-Tidal Sevoflurane Concentration to Maintain Optimal Anesthetic Depth During Cardiopulmonary Bypass: A Meta-Analysis.

Five studies ( n = 129) fulfilled the criteria.

Body temperature was not a significant moderator (difference 0.26 vol%; 95% CI -1.12 to 1.64; p = 0.27).

Higher mean age was associated with lower ETsevo, evidenced by the finding that patients with a mean age of >62.0 years required 0.45 vol% less ETsevo (95% CI -0.78 to -0.13; p = 0.01), and sensitivity analysis revealed a 0.05 vol% decrease per additional year.