Comparison of the change in carotid corrected flow time and stroke volume variation for assessing volume…

ObservationalJournal of clinical monitoring and computing· Apr 2026

Comparison of the change in carotid corrected flow time and stroke volume variation for assessing volume responsiveness in general anesthesia patients: a prospective, observational study.

Yongyong Yang, Min Li, Chenlong Yang … Lu Chen

Perioperative MedicineObservationalQ2IF 2.7

Carotid flow time change predicted fluid responsiveness as well as stroke volume variation

Comparison of the change in carotid corrected flow time and stroke volume variation for assessing volume responsiveness in general anesthesia patients: a prospective, observational study.

Yongyong Yang … Lu Chen

Journal of clinical monitoring and computing · Apr 2026 · Q2 in Anesthesiology

Background

Accurately identifying surgical patients who will have an increase in stroke volume following fluid administration remains challenging when utilizing noninvasive bedside methods.

Purpose

This study aims to compare the value of using ultrasound to measure changes in corrected carotid artery flow time (ΔFTc) with that of using invasive measurements of stroke volume variation (ΔSVV) for assessing volume responsiveness in patients under general anesthesia and mechanical ventilation.

Methods

A total of 91 patients undergoing elective abdominal surgery under general anesthesia were enrolled in this prospective observational study.

n = 91 patients

Results

AUROC of 0.85, similarly accurate at predicting fluid responsiveness as invasive SVV

91.5%

Sensitivity

69.8%

Specificity

More results

A total of 47 (54.0%) patients were fluid responders.

The ΔFTc was 14.5 ± 8.3 ms for responders and 5.7 ± 4.9 ms for non-responders, while the ΔSVV was 3.3 ± 1.4% for responders and 1.7 ± 0.7% for non-responders.

More results

The optimal cutoff values were 7.03 ms for ΔFTc (sensitivity 91.5%, specificity 69.8%) and 2.85% for ΔSVV (sensitivity 95.6%, specificity 72.6%).

A narrower gray zone for ΔFTc, ranging from 7 ms to 12 ms and covering 27 patients, was observed compared with that for ΔSVV, which ranged from 1% to 3% and covered 41 patients.

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Conclusion · 1 of 2

Both the ΔFTc and ΔSVV reliably assessed fluid responsiveness in patients undergoing general anesthesia and mechanical ventilation.

Conclusion · 2 of 2

Noninvasive bedside ultrasound measurement of ΔFTc can serve as an accurate assessment parameter, reflecting the presence of volume responsiveness following rapid fluid administration and showing greater clinical applicability.

Comparison of the change in carotid corrected flow time and stroke volume variation for assessing volume responsiveness in general anesthesia patients: a prospective, observational study.

Comparison of the change in carotid corrected flow time and stroke volume variation for assessing volume responsiveness in general anesthesia patients: a prospective, observational study.

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