Analysis of the Correlation Between Portal Vein Diameter (PVD) and Recurrent Esophagogastric Variceal Bleeding (EGVB) in Patients With Cirrhosis.
Each 1-mm larger portal vein diameter linked to higher risk of recurrent variceal bleeding.
Analysis of the Correlation Between Portal Vein Diameter (PVD) and Recurrent Esophagogastric Variceal Bleeding (EGVB) in Patients With Cirrhosis.
Portal vein diameter (portal vein diameter) is an important and objective marker of portal pressure and may be associated with the risk of recurrent esophagogastric variceal bleeding (esophagogastric variceal bleeding) in patients with cirrhosis.
This study aims to investigate the association between portal vein diameter and the risk of recurrent esophagogastric variceal bleeding in patients with cirrhosis.
This study used a retrospective cohort design, including 1223 patients with cirrhosis discharged from Quanzhou First Hospital between January 2014 and December 2018.
Every 1 mm wider portal vein was associated with a 19% higher rate of recurrent bleeding.
The incidence of recurrent esophagogastric variceal bleeding increased significantly with an increase in portal vein diameter (trend test P=0.023).
Stratified analysis indicated that the risk was particularly significant when portal vein diameter>14 mm (adjusted HR=3.61, P=0.022).
Subgroup analysis showed that, apart from an interaction between age and portal vein diameter (interaction P<0.05), the association between portal vein diameter and recurrent esophagogastric variceal bleeding was consistent across other subgroups (gender, Child-Pugh classification, portal vein thrombosis status) (interaction P>0.05).
An increased portal vein diameter is an independent risk factor for recurrent esophagogastric variceal bleeding in patients with cirrhosis, with a particularly significant increase in risk when portal vein diameter>14 mm.
Monitoring changes in portal vein diameter can provide an important basis for clinical identification of high-risk patients and optimization of portal hypertension management, thereby reducing the incidence of recurrent bleeding events.