The effect of hemodialysis on individual retinal layer thickness.
Intraocular pressure was lower after hemodialysis in end-stage renal disease patients.
The effect of hemodialysis on individual retinal layer thickness.
The aim of this study was to employ newly developed advanced image analysis software to evaluate changes in retinal layer thickness following hemodialysis.
A non-randomized prospective study of patients with end-stage renal disease assessed on the same day before and after hemodialysis.
intraocular pressure was lower after hemodialysis
Of the 31 suitable end-stage renal disease patients treated with hemodialysis who provided consent to participate, seven were unable to complete all evaluations, leaving 24 patients for analysis in the final study group.
Their mean age was 66.67±14.3 years (range: 35-88), and 62.5% were males.
Individual mean retinal layer thickness showed no significant change, including the retinal nerve fiber layer (40.9±6.8 µm to 40.1±5.2 µm, p=.412), the ganglion cell and the inner plexiform layer (68.66±8 µm to 69.03±7.6 µm, p=.639), and the photoreceptor layer (50.26±2.8 µm to 50.32±3.1 µm, p=.869).
Thickness of retinal layers, as assessed by individual segmentation, and central corneal thickness were not affected by hemodialysis treatment, while intraocular pressure was significantly reduced among patients with end-stage renal disease without pre-existing ocular pathology who were undergoing hemodialysis.