PARACENTRAL ACUTE MIDDLE MACULOPATHY AND HENLE FIBER LAYER HEMORRHAGE IN DENGUE FEVER: MULTIMODAL IMAGING…

ReviewRetinal cases & brief reports· Jan 2026

PARACENTRAL ACUTE MIDDLE MACULOPATHY AND HENLE FIBER LAYER HEMORRHAGE IN DENGUE FEVER: MULTIMODAL IMAGING AND REVIEW OF THE LITERATURE.

Bruno F A Ferreira, Gustavo Sakuno, Juliana M Kato … Yoshitaka Nakashima

RetinaReview

Visual acuity improved to 20/20 in one eye after dengue maculopathy.

PARACENTRAL ACUTE MIDDLE MACULOPATHY AND HENLE FIBER LAYER HEMORRHAGE IN DENGUE FEVER: MULTIMODAL IMAGING AND REVIEW OF THE LITERATURE.

Bruno F A Ferreira … Yoshitaka Nakashima

Retinal cases & brief reports · Jan 2026

Purpose

To use multimodal imaging to report a case of dengue fever presenting with Henle fiber layer hemorrhage and acute paracentral acute middle maculopathy.

Methods

Fundus photography and autofluorescence, fluorescein angiography, and optical coherence tomography were acquired over a month, and a literature review of dengue fever-associated maculopathy was performed.

20/20

Results

20/20

normal vision achieved in one eye

More results

A 19-year-old man presented with a sudden loss of vision in both eyes 12 days after experiencing initial systemic symptoms suggestive of dengue fever.

Pupillary light reflex was reduced in both eyes.

Dilated fundoscopic examination revealed optic disk swelling and a small deep Henle fiber layer hemorrhage near the fovea in both eyes.

More results

Immunoglobin M was positive for dengue fever.

“

Conclusion · 1 of 2

Dengue fever-associated maculopathy can present with PAMM and Henle fiber layer hemorrhage. Multimodal imaging is helpful to characterize the extension of the changes in the retina and to monitor its recovery.

Conclusion · 2 of 2

In such cases, structural and functional damage may occur despite treatment with oral steroids.

PARACENTRAL ACUTE MIDDLE MACULOPATHY AND HENLE FIBER LAYER HEMORRHAGE IN DENGUE FEVER: MULTIMODAL IMAGING AND REVIEW OF THE LITERATURE.

PARACENTRAL ACUTE MIDDLE MACULOPATHY AND HENLE FIBER LAYER HEMORRHAGE IN DENGUE FEVER: MULTIMODAL IMAGING AND REVIEW OF THE LITERATURE.

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