Conscious sedation as a potential optimal anesthetic regimen for endoscopic retrograde…

Randomized trialSaudi journal of anaesthesia· Jul 2026

Conscious sedation as a potential optimal anesthetic regimen for endoscopic retrograde cholangiopancreatography in elderly frail patients: A prospective, single-blind, randomized controlled trial.

Chao Li, Na Zeng, Fang Wang … Haijun Hou

Sedation & Anesthetic PharmacologyRandomized trialTreatmentQ2IF 0.9

Conscious sedation reduces adverse cardiovascular events during emergency endoscopic retrograde cholangiopancreatography in frail elderly patients

Conscious sedation as a potential optimal anesthetic regimen for endoscopic retrograde cholangiopancreatography in elderly frail patients: A prospective, single-blind, randomized controlled trial.

Chao Li … Haijun Hou

Saudi journal of anaesthesia · Jul 2026

Purpose

To investigate the impact of adverse cardiovascular events (ACVs) in elderly frail patients undergoing emergency endoscopic retrograde cholangiopancreatography (endoscopic retrograde cholangiopancreatography), and to explore a safe and comfortable anesthetic regimen suitable for this specific population.

Methods

Aged 70-90 years scheduled for emergency endoscopic retrograde cholangiopancreatography were enrolled and randomly divided into two groups: the conscious sedation group (Group S) and the intravenous general anesthesia group (Group A).

n = 108 patients

Results

conscious sedation cut cardiovascular complications by more than half

17%

Group S

40%

Group A

“

Conclusion

Compared with intravenous general anesthesia, conscious sedation can reduce fluctuations in blood pressure and heart rate, and decrease the incidence of adverse cardiovascular events in elderly frail patients undergoing emergency endoscopic retrograde cholangiopancreatography.

Conscious sedation as a potential optimal anesthetic regimen for endoscopic retrograde cholangiopancreatography in elderly frail patients: A prospective, single-blind, randomized controlled trial.

Conscious sedation as a potential optimal anesthetic regimen for endoscopic retrograde cholangiopancreatography in elderly frail patients: A prospective, single-blind, randomized controlled trial.

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