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Case-controlBMC ophthalmology · 2026

Factors leading to high intraocular pressure in Intraocular Device-Associated Uveitis (IDAU): a retrospective nested case-control study from a tertiary uveitis cohort.

Jakkrit Juhong, Thanapong Somkijrungroj, Wijak Kongwattananon … Krit Pongpirul

OphthalmologyCase-control

Intraocular lens malposition strongly associated with high eye pressure in device-associated uveitis

Factors leading to high intraocular pressure in Intraocular Device-Associated Uveitis (IDAU): a retrospective nested case-control study from a tertiary uveitis cohort.

Jakkrit Juhong … Krit Pongpirul

BMC ophthalmology · 2026

Background

Elevated intraocular pressure (IOP) is a major driver of visual morbidity in intraocular device-associated uveitis, but the risk factors that predispose affected patients to IOP elevation remain poorly characterised.

Purpose

We aimed to describe the clinical spectrum of intraocular device-associated uveitis and to identify independent risk factors for elevated IOP in this population, using the Chulalongkorn University Uveitis Cohort (CU 2 C) database.

Methods

This first nested case-control study within the Chulalongkorn University Uveitis Cohort (CU²C) enrolled 375 subjects followed at a tertiary uveitis clinic in Thailand over 8 years (August 2014-June 2022).

n = 375 subjects

Results

Intraocular lens malposition (lens shifted from position) sharply raises odds of high eye pressure

AOR by subgroup · 95% CI

More results

We retrospectively identified 90 subjects who developed intraocular device-associated uveitis.

Three factors were significantly associated with high intraocular pressure in intraocular device-associated uveitis.

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Conclusion · 1 of 2

In this first nested case-control study of intraocular device-associated uveitis, intraocular lens malposition, long axial length (> 25 mm), and older age were independently associated with elevated IOP.

Conclusion · 2 of 2

These findings should inform clinician awareness and post-operative monitoring strategies for high-risk intraocular device-associated uveitis patients.

Post

Factors leading to high intraocular pressure in Intraocular Device-Associated Uveitis (IDAU): a retrospective nested case-control study from a tertiary uveitis cohort.

Intraocular lens malposition strongly associated with high eye pressure in device-associated uveitis

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