Long-Term Observation of Orbital Development in Patients With Retinoblastoma Following Unilateral Enucleation.
After unilateral enucleation, operated orbit volume deficit stabilizes at about 5%.
Long-Term Observation of Orbital Development in Patients With Retinoblastoma Following Unilateral Enucleation.
This study aims to investigate bilateral orbital development differences and influencing factors in retinoblastoma patients undergoing unilateral enucleation.
A retrospective comparative analysis was performed on patients from Beijing Tongren Hospital (January 2011-December 2020).
the treated eye socket's bony space stayed smaller than the healthy side
Average orbital volumes (mm 3 ) for the surgical and nonsurgical sides before surgery were 14,323.81 ± 4596.60 and 14,457.93 ± 4732.26 (p = 0.330).
Postoperative volumes at 3 months were 16,481.84 ± 4034.21 and 16,866.45 ± 3999.71 (p = 0.007).
At 12 months, volumes were 16,798.16 ± 3323.33 and 18,119.16 ± 3840.27 (p = 0.000).
At 36 months, volumes were 18,758.26 ± 2917.35 and 19,973.55 ± 3189.83 (p = 0.000).
Volumetric analysis revealed active orbital development between 3 and 12 months post-enucleation, followed by a significant plateau phase.
The final orbital volume deficit in the surgical orbit stabilized at approximately 5% compared to the non-operated orbit. Hydrogel implants demonstrated a trade-off: potentially reduced volume deficit but higher complication risks.