Long-Term Observation of Orbital Development in Patients With Retinoblastoma Following Unilateral Enucleation.
After unilateral enucleation, operated orbit volume deficit stabilizes at about 5%.
Long-Term Observation of Orbital Development in Patients With Retinoblastoma Following Unilateral Enucleation.
This study aims to investigate bilateral orbital development differences and influencing factors in retinoblastoma patients undergoing unilateral enucleation.
This study aims to investigate bilateral orbital development differences and influencing factors in retinoblastoma patients undergoing unilateral enucleation.
A retrospective comparative analysis was performed on patients from Beijing Tongren Hospital (January 2011-December 2020).
the treated eye socket's bony space stayed smaller than the healthy side
Average orbital volumes (mm 3 ) for the surgical and nonsurgical sides before surgery were 14,323.81 ± 4596.60 and 14,457.93 ± 4732.26 (p = 0.330).
Postoperative volumes at 3 months were 16,481.84 ± 4034.21 and 16,866.45 ± 3999.71 (p = 0.007).
At 12 months, volumes were 16,798.16 ± 3323.33 and 18,119.16 ± 3840.27 (p = 0.000).
At 36 months, volumes were 18,758.26 ± 2917.35 and 19,973.55 ± 3189.83 (p = 0.000).
Volumetric analysis revealed active orbital development between 3 and 12 months post-enucleation, followed by a significant plateau phase.
The final orbital volume deficit in the surgical orbit stabilized at approximately 5% compared to the non-operated orbit. Hydrogel implants demonstrated a trade-off: potentially reduced volume deficit but higher complication risks.