Predictors of enucleation after intra-arterial chemotherapy for retinoblastoma.

Of 305 patients, 26.89% (n=82) underwent enucleation and 73.11% (n=223) did not.

The use of combination chemotherapy was associated with lower odds for enucleation compared with single-agent chemotherapy (OR 0.29, 95% CI 0.11 to 0.80, p=0.016), whereas double-agent chemotherapy was not significantly associated with enucleation (OR 0.90, 95% CI 0.46 to 1.75, p=0.75).