Ocular Ultrasound Elastography for Intraocular Tumors: A Pilot Study.
A 28 kPa stiffness cutoff detected malignant intraocular tumors with high sensitivity.
Ocular Ultrasound Elastography for Intraocular Tumors: A Pilot Study.
Ocular ultrasound elastography (ocular ultrasound elastography) was evaluated as a novel adjunct imaging modality for the characterization of intraocular tumors.
In this prospective pilot study, 12 patients (12 eyes) with clinically and imaging-confirmed intraocular tumors underwent conventional B-scan ultrasonography complemented by strain and shear-wave elastography using a high-frequency linear probe.
found nearly all cancerous eye tumors, with no false alarms
Elastography was successfully performed in all cases without procedure-related complications.
Choroidal melanomas demonstrated high stiffness values (58.4 ± 12.1 kPa), choroidal hemangiomas showed low stiffness (18.9 ± 6.4 kPa), metastases exhibited heterogeneous stiffness profiles (32.6 ± 9.8 kPa), and retinoblastoma showed intermediate stiffness (41.2 kPa).
These findings indicate that ocular ultrasound elastography is a safe, feasible, and reproducible technique that provides quantitative biomechanical information and may enhance the differentiation of benign and malignant intraocular tumors, supporting further validation in larger prospective studies.