Spectrally Resolved (Colour-Coded) Fundus Autofluorescence Using the EIDON System in Vitreoretinal Lymphoma.

Cross-sectionalOphthalmology and therapy· Jul 2026

Spectrally Resolved (Colour-Coded) Fundus Autofluorescence Using the EIDON System in Vitreoretinal Lymphoma.

Alessandro Marchese, Riccardo Sacconi, Matteo Menean … Elisabetta Miserocchi

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Ocular OncologyCross-sectionalDiagnosisQ1IF 4.2

Colour-coded fundus imaging detected all lymphoma-related retinal pigment epithelium detachments tested

Spectrally Resolved (Colour-Coded) Fundus Autofluorescence Using the EIDON System in Vitreoretinal Lymphoma.

Alessandro Marchese … Elisabetta Miserocchi

Ophthalmology and therapy · Jul 2026 · Q1 in Ophthalmology

Background

This study evaluates colour-coded fundus autofluorescence (fundus autofluorescence) in vitreoretinal lymphoma (vitreoretinal lymphoma), which still represents a diagnostic challenge because of the variety of ocular manifestations and difficulties in obtaining a definite diagnosis.

Methods

Retrospective cross-sectional analysis of consecutive patients with vitreoretinal lymphoma studied with colour-coded fundus autofluorescence.

n = 20 eyes

Results

colour-coded imaging found every lymphoma-related fluid pocket under the retina's pigment layer

Colour-coded FAF

4eyes (

Blue/Green FAF

1eyes (

More results

We evaluated 20 eyes from 10 patients affected by vitreoretinal lymphoma.

The agreement among readers on the presence of vitreoretinal lymphoma lesions using colour-coded fundus autofluorescence was excellent.

The classic granular appearance was similarly detected in 13/13 eyes across all fundus autofluorescence modalities.

“

Conclusion · 1 of 2

Colour-coded fundus autofluorescence can recognize the classic features of vitreoretinal lymphoma.

Conclusion · 2 of 2

As a complementary imaging modality, colour-coded fundus autofluorescence may facilitate the recognition of retinitis-like lesions, lymphomatous retinal pigment epithelium detachments, and minor fluorophores compared with other fundus autofluorescence types.

Spectrally Resolved (Colour-Coded) Fundus Autofluorescence Using the EIDON System in Vitreoretinal Lymphoma.

Spectrally Resolved (Colour-Coded) Fundus Autofluorescence Using the EIDON System in Vitreoretinal Lymphoma.

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