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New research · Ophthalmology
Ophthalmology and therapy · 1d
Cross-sectionalOphthalmology and therapy · 2026

Spectrally Resolved (Colour-Coded) Fundus Autofluorescence Using the EIDON System in Vitreoretinal Lymphoma.

Alessandro Marchese, Riccardo Sacconi, Matteo Menean … Elisabetta Miserocchi
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OphthalmologyCross-sectional

Colour-coded fundus imaging detected all lymphoma-related retinal pigment epithelium detachments tested

Spectrally Resolved (Colour-Coded) Fundus Autofluorescence Using the EIDON System in Vitreoretinal Lymphoma.

Alessandro Marchese … Elisabetta Miserocchi
Ophthalmology and therapy · 2026
Background

This study evaluates colour-coded fundus autofluorescence (fundus autofluorescence) in vitreoretinal lymphoma (vitreoretinal lymphoma), which still represents a diagnostic challenge because of the variety of ocular manifestations and difficulties in obtaining a definite diagnosis.

Methods

Retrospective cross-sectional analysis of consecutive patients with vitreoretinal lymphoma studied with colour-coded fundus autofluorescence.

n = 20 eyes
Results

colour-coded imaging found every lymphoma-related fluid pocket under the retina's pigment layer

Colour-coded FAF
4eyes (
Blue/Green FAF
1eyes (
More results

We evaluated 20 eyes from 10 patients affected by vitreoretinal lymphoma.

The agreement among readers on the presence of vitreoretinal lymphoma lesions using colour-coded fundus autofluorescence was excellent.

The classic granular appearance was similarly detected in 13/13 eyes across all fundus autofluorescence modalities.

“
Conclusion · 1 of 2

Colour-coded fundus autofluorescence can recognize the classic features of vitreoretinal lymphoma.

Conclusion · 2 of 2

As a complementary imaging modality, colour-coded fundus autofluorescence may facilitate the recognition of retinitis-like lesions, lymphomatous retinal pigment epithelium detachments, and minor fluorophores compared with other fundus autofluorescence types.

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