Role of Menopausal Hormone Therapy on Strabismus, Strabismus Surgery, and Reoperation Rates. | ScholarDeck

Paper

Role of Menopausal Hormone Therapy on Strabismus, Strabismus Surgery, and Reoperation Rates.

New research · Ophthalmology

American journal of ophthalmology · 1mo

Cohort studyAmerican journal of ophthalmology· Jul 2026

Role of Menopausal Hormone Therapy on Strabismus, Strabismus Surgery, and Reoperation Rates.

Akshara R Legala, Takashi Nishida, Ashley Liang … Jolene C Rudell

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Pediatric OphthalmologyCohort studyQ1IF 4.2

Menopausal hormone therapy linked to higher risk of strabismus surgery.

Role of Menopausal Hormone Therapy on Strabismus, Strabismus Surgery, and Reoperation Rates.

Akshara R Legala … Jolene C Rudell

American journal of ophthalmology · Jul 2026 · Q1 in Ophthalmology

Purpose

To evaluate the association between menopausal hormone therapy (menopausal hormone therapy) and strabismus outcomes in menopausal women.

Methods

Female patients in Epic Cosmos with a first menopause diagnosis between ages 44 and 60 years from January 1, 2010, to October 31, 2025 were included.

Results

hormone therapy users had higher odds of needing eye-alignment surgery

HR by subgroup · 95% CI

More results

Among 2,154,255 menopausal patients, 197,576 (9.2%) received menopausal hormone therapy and 1,956,679 (90.8%) did not.

Mean age at menopause diagnosis was 54.9 (4.1) years, and 67.3% identified as White.

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Conclusion

Menopausal hormone therapy was associated with increased risk of strabismus diagnosis and surgery in menopausal women, suggesting a potential relationship between menopausal hormone therapy and ocular alignment outcomes.

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