Effect of cataracts on systemic factor prediction from fundus images.

We included 67 patients (101 eyes; 37.3% male) with a mean age of 72.5 ± 11.4 years.

More than half of the participants were receiving treatment for hypertension, diabetes mellitus, or were using steroids.

Among all analyses, only chronological age was significantly associated with retinal age, both preoperatively (β = 0.48, P = 8.6 × 10 - 8 ) and postoperatively (β = 0.47, P = 3.1 × 10 - 9 ).

These findings remained consistent in a subgroup analysis of patients without fundus diseases who underwent only cataract surgery (P = 3.8 × 10 - 10 ).