Metagenomic sequencing found E. hellem DNA dominating a corneal infection sample
Bilateral Encephalitozoon hellem Keratoconjunctivitis With Microsporidial Spores in Parrot Feces.
Xu Wang … Li Li
Cureus · 2026
Methods
Metagenomic next-generation sequencing (mNGS) of the same specimen detected 9,684 reads assigned to E. hellem , with a relative abundance of approximately 98% and genome coverage of 63%, supporting the diagnosis.
Results
98%
these DNA fragments made up nearly all germs found in the sample
More results
We describe bilateral Encephalitozoon hellem keratoconjunctivitis in a 39-year-old immunocompetent woman with two years of daily close contact with a pet parrot.