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Cross-sectionalGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026

Inner retinal structure and intraocular pressure in children with obesity.

Julia Dezor-Garus, Elżbieta Niechciał, Andrzej Kędzia, Anna Gotz-Więckowska

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OphthalmologyCross-sectional

Childhood obesity is associated with higher intraocular pressure.

Inner retinal structure and intraocular pressure in children with obesity.

Julia Dezor-Garus … Anna Gotz-Więckowska

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026

Purpose

To test whether pediatric obesity is associated with inner retinal structure and intraocular pressure (IOP) changes, and whether insulin resistance (insulin resistance) is associated with additional ophthalmic differences within the obesity subgroup.

Methods

This cross-sectional study enrolled 202 children aged 6-18 years, including 92 with obesity and 110 controls.

n = 202 children

2.48

Results

2.48

mmHg

children with obesity had higher eye pressure, a possible early warning sign

n = 202 children

More results

In the primary age- and sex-adjusted models, obesity was associated with higher IOP and lower average, temporal, and nasal retinal nerve fiber layer thickness.

More results

After additional adjustment for axial length and spherical equivalent, the association with higher IOP remained robust, whereas retinal nerve fiber layer differences were attenuated; only the temporal retinal nerve fiber layer difference remained statistically significant.

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Conclusion · 1 of 3

In this cross-sectional pediatric cohort, obesity was associated with higher IOP, and this association remained stable after adjustment for ocular biometry.

Conclusion · 2 of 3

retinal nerve fiber layer differences were sensitive to biometry and magnification correction, whereas ganglion cell and inner plexiform layer thickness did not differ significantly.

Conclusion · 3 of 3

insulin resistance was not independently associated with OCT or IOP parameters within the obesity subgroup. Longitudinal studies are needed to determine the clinical relevance of these findings.

Post

Inner retinal structure and intraocular pressure in children with obesity.

Childhood obesity is associated with higher intraocular pressure.

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