Marin-Amat syndrome: a comprehensive review of pathophysiology, clinical presentation, and management.

Twenty articles met inclusion criteria, comprising 37 patients.

The mean age was 55.8 ± 23.3 years.

Electrophysiologic and clinical descriptions supported active orbicularis oculi co-contraction consistent with post-paralytic synkinesis, with a margin reflex distance-1 reduction of roughly 0.5-2.5 mm on jaw opening.

Botulinum toxin type A directed at the orbicularis oculi produced effective but transient control.