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New research · Ophthalmology
Veterinary ophthalmology · 5d
Animal / preclinicalVeterinary ophthalmology · 2026

Evaluation of Rose-Bengal Photodynamic Antimicrobial Therapy for Refractory Infectious Keratitis in Dogs and Cats (22 Cases).

Frank Famose, Guillaume Cazalot, Marie-Claire Robin
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OphthalmologyAnimal / preclinical

All 22 eyes with resistant corneal infections healed fully within 30 days after adjunctive photodynamic therapy

Evaluation of Rose-Bengal Photodynamic Antimicrobial Therapy for Refractory Infectious Keratitis in Dogs and Cats (22 Cases).

Frank Famose … Marie-Claire Robin
Veterinary ophthalmology · 2026
Purpose

To report the clinical outcomes of Rose Bengal Photodynamic Antimicrobial Therapy (Rose Bengal Photodynamic Antimicrobial Therapy) as adjunctive therapy for progressive infectious keratitis (infectious keratitis) in companion animals.

Methods

ANIMALS STUDIED: A retrospective descriptive review was performed on 22 eyes (14 dogs, 8 cats from private owners) treated with Rose Bengal Photodynamic Antimicrobial Therapy after failure of initial medical therapy between December 2024 and September 2025.

n = 22 eyes
Results

eyes with fully healed cornea within this many days - no case took longer

Dogs (median)
9days
Cats (mean)
14days
More results

Clinical improvement was documented in all patients.

No significant adverse effects occurred.

None of the eyes required additional surgery.

“
Conclusion · 1 of 3

Rose Bengal Photodynamic Antimicrobial Therapy appears to be safe, well-tolerated, and associated with rapid epithelial closure in refractory infectious keratitis.

Conclusion · 2 of 3

The treatment may reduce reliance on aggressive antibiotic protocols and lower the likelihood of surgical intervention.

Conclusion · 3 of 3

Larger prospective studies are needed to further define indications, safety, and comparative efficacy of Rose Bengal Photodynamic Antimicrobial Therapy in veterinary patients.

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