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New research · Anesthesiology
Jornal de pediatria · 1w
Cohort studyJornal de pediatria · 2026

Incidence and risk factors for intraoperative hypotension in neonates undergoing non-cardiac surgery: a retrospective cohort study.

Jialian Zhao, Chunyi Jin, Guihang An … Yue Jin
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AnesthesiologyCohort study

Intraoperative hypotension occurred in most neonates undergoing non-cardiac surgery

Incidence and risk factors for intraoperative hypotension in neonates undergoing non-cardiac surgery: a retrospective cohort study.

Jialian Zhao … Yue Jin
Jornal de pediatria · 2026
Background

Intraoperative hypotension is associated with adverse postoperative outcomes, yet evidence in the neonatal population is limited.

Purpose

This study aimed to investigate the incidence, risk factors, and prognostic significance of intraoperative hypotension in this population.

Methods

This single-center retrospective study included 1712 neonates undergoing non-cardiac surgery from 2020 to 2025 at a tertiary children's hospital in China.

n = 1712 neonates
Results

most newborns had a marked drop in blood pressure during surgery

OR by subgroup · 95% CI
null = 1
luded American Society of
1.36
emergency surgery
1.32
surgery duration > 60 min
1.46
thoracic surgery
1.73
preoperative congenital heart disease
1.38
More results

Higher gestational age (OR = 0.936, 95% CI: 0.891-0.983, P = 0.008) and neurosurgery (OR = 0.566, 95% CI: 0.385-0.832, P = 0.004) were protective factors.

Intraoperative hypotension was associated with prolonged postoperative recovery and increased acute kidney injury and intraventricular hemorrhage (all P < 0.05).

“
Conclusion · 1 of 2

Intraoperative hypotension is highly prevalent in neonatal non-cardiac surgery and was associated with short-term outcomes.

Conclusion · 2 of 2

Identified risk and protective factors may guide perioperative hemodynamic optimization in this vulnerable population.

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