Post

New research · Nephrology
PloS one · 1d
Cohort studyPloS one · 2026

Predictive value of complete blood cell count-based inflammatory markers for peritonitis risk in peritoneal dialysis patients: A multicenter cohort study.

Xue Li, Wenlong Qiu, Qingdong Xu … Na Tian
Read paper
NephrologyCohort study

Elevated systemic immune-inflammatory index is associated with higher peritonitis risk.

Predictive value of complete blood cell count-based inflammatory markers for peritonitis risk in peritoneal dialysis patients: A multicenter cohort study.

Xue Li et al. · PloS one · 2026
Background

Peritonitis is a serious complication of peritoneal dialysis (PD).

Purpose

This multicenter cohort study aimed to evaluate and compare these indices to identify the best predictor of PDAP.

Methods

We retrospectively enrolled 2,036 PD patients from 10 centers.

n = 147 patients
Results
Higher inflammatory index means more than double the risk of abdominal lining inflammation
n = 147 patients
More results

The median age was 51.0 years, 55.01% were male, and median dialysis vintage was 49.47 months.

Diabetes prevalence was 21.02%.

Over the follow-up, 147 patients (7.22%) developed peritonitis.

Among the indices evaluated, PIV, SII, and PLR showed significant nonlinear associations with peritonitis risk (all P < 0.05).

“
Conclusion · 1 of 2

Elevated PIV, SII, and PLR levels at PD initiation independently predict higher peritonitis risk.

Conclusion · 2 of 2

Although their discriminative ability is moderate, these routine, cost-effective indices may aid risk stratification and help identify patients needing closer monitoring or preventive interventions.

Read paper
0 comments

No comments yet. Be the first.

Related papers

LatestFoundational
Cohort Study
hazard ratio 4.00
high genetic risk and severe CKM syndrome meant a much higher risk of knee arthritis
Cohort Study
11.1%
hospitalizations for heart inflammation in dialysis patients that included severe heart issues
Cohort Study
HR 4.00
Severe kidney scarring linked to about 4-fold higher rate of graft failure
Guideline
almost 30%
people with Von-Hippel Lindau syndrome are affected by kidney cancer
Cohort Study
14.0%
About 1 in 7 survivors without prior risk factors had persistent kidney damage
Guideline
“This consensus aims to clarify for which patients renal denervation may be a viable therapeutic option, identify the main clinical and procedural considerations for its implementation, and promote its optimal and safe use through appropriate patient selection and multidisciplinary evaluation.”
Cohort Study
-41.5 mg/dL
GLP-1 RAs were associated with lower total cholesterol
Guideline
approximately 80%
how many people with early AL amyloidosis are expected to live for 5 years