Targeted Treatment of Agitation in Alzheimer's Dementia: Prioritizing Function and Safety Over Sedation and Other Serious Harms.

Clinicians across the spectrum of care settings frequently encounter agitation but often lack practical clinical guidance.

In April 2026, a consensus panel of clinical experts reviewed the literature and developed guidance for managing agitation in Alzheimer's dementia.

Treatment should prioritize reduction of patient and caregiver distress and preservation of function rather than mere sedation.

Finally, setting-specific considerations were discussed.