Quadratus Lumborum Block versus Thoracic Paravertebral Block for Postoperative Recovery Quality after…

Randomized trialPain and therapy· Aug 2026

Quadratus Lumborum Block versus Thoracic Paravertebral Block for Postoperative Recovery Quality after Percutaneous Nephrolithotomy: A Randomized Noninferiority Trial.

Wenjun Lin, Qingfu Zhang, Feifei Zheng … Guisheng Ding

Regional AnesthesiaRandomized trialQ1IF 4.0

Anterior quadratus lumborum block was noninferior to thoracic paravertebral block after percutaneous nephrolithotomy.

Quadratus Lumborum Block versus Thoracic Paravertebral Block for Postoperative Recovery Quality after Percutaneous Nephrolithotomy: A Randomized Noninferiority Trial.

Wenjun Lin … Guisheng Ding

Pain and therapy · Aug 2026 · Q1 in Anesthesiology

Purpose

We aimed to determine whether anterior quadratus lumborum block (quadratus lumborum block) at the lateral supra-arcuate ligament is noninferior to thoracic paravertebral block (thoracic paravertebral block) for postoperative recovery quality after percutaneous nephrolithotomy (percutaneous nephrolithotomy).

Methods

A total of 72 adults (American Society of Anesthesiologists physical status I-II) undergoing elective unilateral percutaneous nephrolithotomy were randomized to quadratus lumborum block (n = 36) or thoracic paravertebral block (n = 36).

n = 72 adults

2

Results

2

less morphine needed and fewer hypotension episodes with anterior quadratus lumborum block

n = 72 adults

More results

Hypotension occurred in 4 of 35 patients (11%) with quadratus lumborum block versus 13 of 36 (36%) with thoracic paravertebral block (relative risk, 0.32; 95% CI, 0.11 to 0.88; p = 0.015).

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Conclusion · 1 of 2

Anterior quadratus lumborum block was noninferior to thoracic paravertebral block for postoperative recovery quality after percutaneous nephrolithotomy.

Conclusion · 2 of 2

Associated reductions in pain and opioid use, and a lower observed incidence of hypotension, seen in secondary and exploratory analyses, are hypothesis-generating and warrant confirmation. Graphical abstract available for this article.

Quadratus Lumborum Block versus Thoracic Paravertebral Block for Postoperative Recovery Quality after Percutaneous Nephrolithotomy: A Randomized Noninferiority Trial.

Quadratus Lumborum Block versus Thoracic Paravertebral Block for Postoperative Recovery Quality after Percutaneous Nephrolithotomy: A Randomized Noninferiority Trial.

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