Long-term Oncological Outcomes of Retzius-sparing Versus Anterior Robot-assisted Radical Prostatectomy: Post…

Cohort studyEuropean urology oncology· Sep 2026

Long-term Oncological Outcomes of Retzius-sparing Versus Anterior Robot-assisted Radical Prostatectomy: Post Hoc Analysis of a Randomized Cohort.

Alfonso Santangelo, Wooju Jeong, Caro Silvani … Firas Abdollah

Robotic & Minimally Invasive SurgeryCohort studyTreatmentQ1IF 5.9

Retzius-sparing prostatectomy raises risk of cancer progression versus anterior approach

Long-term Oncological Outcomes of Retzius-sparing Versus Anterior Robot-assisted Radical Prostatectomy: Post Hoc Analysis of a Randomized Cohort.

Alfonso Santangelo … Firas Abdollah

European urology oncology · Sep 2026 · Q1 in Surgery

Background

The Retzius-sparing (retzius-sparing) robot-assisted radical prostatectomy (robot-assisted radical prostatectomy) was proposed in 2010 to enhance early postoperative continence recovery.

Purpose

This study reports the long-term oncological outcomes of a randomized controlled trial originally designed to compare early continence recovery in patients treated using the retzius-sparing versus standard (anterior) approach.

Methods

Were randomized 1:1 to the anterior or retzius-sparing approach (n = 60 per arm).

n = 120 men

Results

After adjustment, progression risk was 2.64 times higher with Retzius-sparing surgery.

RS

80.2%

More results

At 5 yr, PFS was 80.2% in the retzius-sparing group versus 91.1% in the anterior group (p = 0.01).

“

Conclusion

Although retzius-sparing robot-assisted radical prostatectomy provides superior early continence outcomes, patients randomized to this approach experienced less favorable long-term oncological control, potentially because of the increased technical demands of the procedure.

Long-term Oncological Outcomes of Retzius-sparing Versus Anterior Robot-assisted Radical Prostatectomy: Post Hoc Analysis of a Randomized Cohort.

Long-term Oncological Outcomes of Retzius-sparing Versus Anterior Robot-assisted Radical Prostatectomy: Post Hoc Analysis of a Randomized Cohort.

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