Near-Infrared Spectroscopy (NIRS) for Early Postoperative Monitoring of Graft Oxygenation in Living Donor…

ObservationalClinical transplantation· Jun 2026

Near-Infrared Spectroscopy (NIRS) for Early Postoperative Monitoring of Graft Oxygenation in Living Donor Liver Transplantation: A Prospective Observational Study.

Ravshan Ibadov, Konstantin Semash, Azimjon Usmonov … Oybek Omonov

Transplant SurgeryObservationalQ2IF 1.8

Near-infrared spectroscopy liver oxygen saturation below 72% flagged perfusion complications after transplant

Near-Infrared Spectroscopy (NIRS) for Early Postoperative Monitoring of Graft Oxygenation in Living Donor Liver Transplantation: A Prospective Observational Study.

Ravshan Ibadov … Oybek Omonov

Clinical transplantation · Jun 2026

Background

Near-infrared spectroscopy (near-infrared spectroscopy) provides a continuous and noninvasive method for assessing hepatic graft oxygenation.

Purpose

To determine the clinical utility of near-infrared spectroscopy for early postoperative graft monitoring after living donor liver transplantation and to define physiological hepatic LSrO 2 values in healthy individuals.

Methods

This prospective observational study included 83 adult living donor liver transplantation recipients and 30 healthy volunteers.

n = 83 adult

Results

Below this graft oxygen saturation cutoff, complication detection was 68.8% sensitive, 82.1% specific.

68.8%

Sensitivity

82.1%

Specificity

More results

Healthy volunteers demonstrated a mean hepatic LSrO2 of 76.8 ± 0.89 (95% CI: 76.47-77.13).

Living donor liver transplantation recipients had significantly lower LSrO 2 values (74.49 ± 3.74, 95% CI: 73.66-75.32; p < 0.001).

More results

LSrO 2 correlated positively with hemoglobin (r = 0.507 at 24 h), hepatic artery flow velocity (r = 0.328 at 24 h), and platelet count (r = 0.401 at 48 h), and inversely with lactate (r = -0.329 at 24 h).

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Conclusion · 1 of 2

Near-infrared spectroscopy demonstrated promise as a reliable adjunct method for early postoperative graft monitoring following living donor liver transplantation. LSrO 2 values below 72% may indicate early perfusion impairment.

Conclusion · 2 of 2

Establishing reference LSrO 2 values in healthy volunteers enhances the interpretability of postoperative measurements and supports the integration of near-infrared spectroscopy into standard monitoring protocols.

Near-Infrared Spectroscopy (NIRS) for Early Postoperative Monitoring of Graft Oxygenation in Living Donor Liver Transplantation: A Prospective Observational Study.

Near-Infrared Spectroscopy (NIRS) for Early Postoperative Monitoring of Graft Oxygenation in Living Donor Liver Transplantation: A Prospective Observational Study.

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