Impact of frailty and physiological severity on early and medium-term surgical outcomes after open abdomen.

Of 3,103 emergency laparotomies, 115 patients (3.7%) required open abdomen (69.6% males; median age: 62 y).

Median time to definitive closure was three days (IQR: 2-4.75).

In-hospital mortality was 47%; overall 49.6%, including 22.6% within 48 hours.

Frailty indices showed no significant association with mortality or survival ( p = 0.11; p = 0.081).