Lactate abnormalities during intravenous linezolid therapy in hospitalized children: a brief report. | ScholarDeck

Paper

Lactate abnormalities during intravenous linezolid therapy in hospitalized children: a brief report.

New research · Pediatrics

European journal of pediatrics · 1w

Cohort studyEuropean journal of pediatrics· May 2026

Lactate abnormalities during intravenous linezolid therapy in hospitalized children: a brief report.

Taha Ikram Ozsumbul, Osman Oguz Demir, Kubra Aykac, Yasemin Ozsurekci

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Pediatric Infection & VaccinationCohort studyClinical practiceQ1IF 3.2

Over half of children on IV linezolid developed lactate abnormalities

Lactate abnormalities during intravenous linezolid therapy in hospitalized children: a brief report.

Taha Ikram Ozsumbul … Yasemin Ozsurekci

European journal of pediatrics · May 2026 · Q1 in Pediatrics

Background

Linezolid is commonly used in children for the treatment of severe gram-positive infections; however, data on metabolic adverse effects remain limited.

Methods

We evaluated lactate abnormalities in pediatric patients receiving intravenous linezolid.

n = 215 children

55.8%

Results

55.8%

more than half developed abnormal lactate levels on IV linezolid

n = 215 children

“

Conclusion

These findings suggest that host-related factors may influence susceptibility to lactate disturbances during linezolid therapy and support careful clinical monitoring in selected pediatric populations.

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