Ultrasound-guided hydrostatic enema reduction for intussusception in children younger than 12 months: a…

Meta-analysisPediatric surgery international· Jul 2026

Ultrasound-guided hydrostatic enema reduction for intussusception in children younger than 12 months: a systematic review and meta-analysis.

Amani N Alansari, Marwa Messaoud, Mohamed Sayed Zaazouee … Ayman Albaghdady

Pediatric SurgeryMeta-analysisTreatmentQ2IF 1.8

Ultrasound-guided hydrostatic enema reduces intussusception successfully in most infants under 12 months

Ultrasound-guided hydrostatic enema reduction for intussusception in children younger than 12 months: a systematic review and meta-analysis.

Amani N Alansari … Ayman Albaghdady

Pediatric surgery international · Jul 2026 · Q2 in Surgery

Background

Intussusception is the most common cause of bowel obstruction in infancy and may lead to substantial morbidity.

Methods

A systematic search was performed from database inception through January 2026.

n = 2656 infants

Results

reduction succeeded without surgery in most infants treated

80%

Success

8%

Recurrence

2%

Perforation

More results

Twenty-two studies, including 2656 infants, met the inclusion criteria.

Subgroup analysis demonstrated no significant effect of sedation status or study design on outcomes, whereas income level was significantly associated with perforation risk.

Substantial heterogeneity was observed across outcomes.

Overall certainty of evidence was low.

“

Conclusion · 1 of 2

UGHR demonstrates a clinically meaningful success rate with an acceptable safety profile in infants under 12 months, supporting its role as a safe and effective non-surgical treatment in hemodynamically stable patients.

Conclusion · 2 of 2

Standardized global protocols and high-quality prospective multicenter studies are needed to optimize outcomes and strengthen the evidence base.

Ultrasound-guided hydrostatic enema reduction for intussusception in children younger than 12 months: a systematic review and meta-analysis.

Ultrasound-guided hydrostatic enema reduction for intussusception in children younger than 12 months: a systematic review and meta-analysis.

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