Maternal Thyroid Dysfunction During Pregnancy and Childhood Autism or Other Developmental Outcomes.

Thyroid stimulating hormone (thyroid stimulating hormone) and free thyroxine (FT4) were also examined as exposures.

Of 285 children included in analyses, 28.8% were diagnosed with autism spectrum disorder (n = 82; female = 27) and 14.7% with non-TD (n = 42; female = 19).

Significant relationships were also found between hypothyroid conditions and non-TD, and between first trimester thyroid stimulating hormone and autism spectrum disorder.

There was no evidence of a relationship between either thyroid stimulating hormone or FT4 and preschool Social Responsiveness Scale scores.