Analysis of risk factors for severe acute poisoning in children.
Gastric lavage associated with lower odds of severe acute poisoning in children
Analysis of risk factors for severe acute poisoning in children.
To identify independent risk factors for the progression of acute poisoning to severe cases in children, and to provide a basis for early clinical identification and intervention.
A retrospective study was conducted to collect the clinical data of hospitalized children with acute poisoning at Tianshui First People's Hospital from January 1, 2018 to December 31, 2025.
gastric lavage was linked to lower odds of severe poisoning
Two deaths occurred, with a case fatality rate of 0.3%.
The difference across age groups was statistically significant ( χ 2 = 10.451, P = 0.015), with adolescents accounting for the highest proportion of severe cases (48.1%, 38/79).
The ROC curve showed an area under the curve (AUC) of 0.710 (95% CI: 0.645-0.775).
Gastric lavage associated with a lower risk of severe poisoning in this pediatric cohort. When strictly indicated, it may remain a procedure of clinical value.
Left-behind children and those with self-poisoning are high-risk populations requiring enhanced family supervision, early recognition, and psychological intervention.
The association between antidote use and increased risk of severe poisoning likely reflects confounding by indication, and should not delay necessary antidotal therapy.