68 Ga-FAPI PET/CT for Differentiation of Malignant Peripheral Nerve Sheath Tumors, Neurofibromas, and Schwannomas.

Malignant peripheral nerve sheath tumors showed significantly higher 68 Ga-FAPI uptake compared with benign peripheral nerve sheath tumors.

Neurofibromas showed higher 68 Ga-FAPI uptake compared with schwannomas.

In dynamic imaging, time to peak of malignant peripheral nerve sheath tumors and neurofibromas was prolonged compared with schwannomas.

Fibroblast activation protein expression was strong in malignant peripheral nerve sheath tumors and moderate in benign peripheral nerve sheath tumors.