Amplification and Overexpression of Cyclin D1 in Epstein-Barr Virus-Positive Inflammatory Follicular Dendritic Cell Sarcoma: A Targeted Next-Generation Sequencing Study.

The cohort included 13 men and 18 women, with a mean age of 62.6 years (range, 36-84).

Tumors arose in the spleen (n = 20), liver (n = 8), colon (n = 2), and pancreas (n = 1), with a mean tumor size of 5.8 cm (range, 1.4-11.7).

No significant clinicopathologic difference was present between TSO500-positive and TSO500-negative tumors.

Notably, splenic origin was associated with female predominance (P = .011) and larger tumor size (P = .048).