ARTERIAL REMODELING ON KNEE MRI AND CARTILAGE T2 RELAXATION TIME: DATA FROM THE OSTEOARTHRITIS INITIATIVE.
Wider, thicker popliteal artery walls linked to higher knee cartilage T2 values
ARTERIAL REMODELING ON KNEE MRI AND CARTILAGE T2 RELAXATION TIME: DATA FROM THE OSTEOARTHRITIS INITIATIVE.
Popliteal artery remodeling may contribute to knee OA through altered periarticular and subchondral perfusion.
To evaluate cross-sectional and longitudinal associations between baseline MRI-derived popliteal artery parameters and cartilage T2 relaxation time in OAI participants.
This retrospective longitudinal analysis included 4,447 OAI participants with baseline right-knee cartilage T2 measurements; 3,854 and 3,560 participants had 12- and 24-month follow-up T2 data, respectively.
thicker, larger popliteal artery walls track with higher, worse cartilage T2
Mean age was 61.1 ± 9.1 years, 2,612/4,447 (58.7%) participants were female, and mean BMI was 28.5 ± 4.8 kg/m2.
Mean wall thickness was associated only with lateral tibial (β=0.13, 95% CI=0.04 to 0.23; p=0.006) and lateral femoral T2 (β=0.11, 95% CI=0.01 to 0.21; p=0.039).
Baseline arterial parameters were not associated with 12- or 24-month T2 change after baseline T2 adjustment.
Effect sizes were generally larger in KL≥2.
Automated knee MRI-derived popliteal artery size and remodeling parameters were associated with baseline cartilage T2 relaxation time, particularly in knees with radiographic OA, but did not predict short-term T2 change.