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Correlation of Preoperative Diffusion-weighted Magnetic Resonance Imaging-based Virtual Elastography with Intraoperative Quantitative Tumor Stiffness in Meningiomas.

New research · Radiology

Neurologia medico-chirurgica · 2w

Cross-sectionalNeurologia medico-chirurgica· Aug 2026

Correlation of Preoperative Diffusion-weighted Magnetic Resonance Imaging-based Virtual Elastography with Intraoperative Quantitative Tumor Stiffness in Meningiomas.

Mitsuyoshi Abe, Yuki Sakaeyama, Ryo Matsuzaki … Nobuo Sugo

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NeuroradiologyCross-sectionalQ1IF 1.8

Diffusion-based virtual elastography correlates with meningioma stiffness measured at surgery

Correlation of Preoperative Diffusion-weighted Magnetic Resonance Imaging-based Virtual Elastography with Intraoperative Quantitative Tumor Stiffness in Meningiomas.

Mitsuyoshi Abe … Nobuo Sugo

Neurologia medico-chirurgica · Aug 2026

Background

Tumor stiffness strongly influences exposure, extent of resection, operative time, and approach in meningioma surgery, but magnetic resonance imaging-based prediction still relies mainly on qualitative assessment.

r = -0.655

Results

r = -0.655

lower diffusion-derived values signaled firmer tumors, higher values softer ones

n = 33 patients

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Lower diffusion-derived stiffness surrogate values were associated with firmer tumors, whereas higher values were associated with softer tumors.

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Conclusion

These findings indicate that diffusion-weighted magnetic resonance imaging-based virtual elastography may provide a noninvasive, quantitative preoperative surrogate marker for estimating the stiffness of selected solid components of meningiomas and may offer adjunctive information for surgical planning.

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