Prenatal magnetic resonance imaging findings of tuberous sclerosis complex in fetuses.
Magnetic resonance imaging "bright spot" sign strongly suggests fetal cardiac rhabdomyoma in tuberous sclerosis complex.
Prenatal magnetic resonance imaging findings of tuberous sclerosis complex in fetuses.
This study aimed to characterize the prenatal imaging features of brain and cardiac lesions associated with tuberous sclerosis complex (tuberous sclerosis complex), with particular focus on fetal magnetic resonance imaging (magnetic resonance imaging) findings, and to explore the complementary role of fetal magnetic resonance imaging, fetal echocardiography, and genetic testing in prenatal evaluation.
This retrospective study analyzed prenatal neurocardiac magnetic resonance imaging findings in fetuses diagnosed with tuberous sclerosis complex or cardiac rhabdomyomas through genetic and/or clinical assessment between 2018 and 2025.
Cortical dysplasia included cortical tubers and white matter migrational abnormalities.
Subependymal giant cell astrocytoma appears hypointense on T2WI and hyperintense on T1WI.
According to our research, T1WI was superior to T2WI in demonstrating cortical dysplasia.
Intracranial lesions in tuberous sclerosis complex manifest as hyperintense on T1WI (contrasting with the dark background of white matter), a phenomenon often referred to as the "bright spot" sign.
The "bright spot" sign on magnetic resonance imaging has significant diagnostic value for fetal tuberous sclerosis complex, particularly for identifying cortical dysplasia and cardiac rhabdomyoma.
In cases of suspected tuberous sclerosis complex or cardiac rhabdomyoma, combining prenatal ultrasound with magnetic resonance imaging enhances diagnostic accuracy, facilitating better clinical management.