Accuracy of PET/CT for the Detection of Synchronous Malignant Lesions in Patients With Endoscopically…

Cohort studySurgical laparoscopy, endoscopy & percutaneous techniques· Jun 2026

Accuracy of PET/CT for the Detection of Synchronous Malignant Lesions in Patients With Endoscopically Obstructive Colorectal Cancer.

Cemil Burak Kulle, Mehmet Iskender Yıldırım, Halil Alper Bozkurt … Adem Bayraktar

Colon & Rectal SurgeryCohort studyDiagnosisQ2IF 1.2

PET/CT detected all synchronous malignant lesions in the proximal colon before surgery

Accuracy of PET/CT for the Detection of Synchronous Malignant Lesions in Patients With Endoscopically Obstructive Colorectal Cancer.

Cemil Burak Kulle … Adem Bayraktar

Surgical laparoscopy, endoscopy & percutaneous techniques · Jun 2026 · Q2 in Surgery

Purpose

This study aimed to assess the diagnostic performance of positron emission tomography/computed tomography (PET/CT) in detecting synchronous malignant lesions in the proximal colon in endoscopically obstructive left-sided colorectal cancer.

Methods

All patients with a biopsy-proven left-sided endoscopically obstructive colorectal cancer who had a preoperative PET/CT scan and a postoperative total colonoscopy within 6 months after the index surgery between January 2015 and July 2024 at a comprehensive cancer center were enrolled into the study.

n = 90 patients

Results

Sensitivity and negative predictive value were both 100% for finding synchronous cancers.

Sensitivity

100%

Specificity

94.4%

PPV

44.4%

NPV

100%

More results

Out of 90 patients, 50 (55.6%) were male with a mean age of 62.46±10.81 years.

The obstructing malignant lesions detected on colonoscopy were located in the rectum, n=8 (8.9%), rectosigmoid junction, n=29 (32.2%), sigmoid colon, n=31 (34.4%), descending colon, n=16 (17.8%), and distal part of the transverse colon, n=6 (6.7%).

More results

Nine areas of abnormal fluorodeoxyglucose (fluorodeoxyglucose) uptake on PET/CT in the proximal part of the colon with a mean SUVmax value of 19.23 (range: 6.4-42) were identified in 6 patients.

Four patients with synchronous lesions on PET/CT underwent a total colectomy.

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Conclusion · 1 of 2

PET/CT demonstrated a high sensitivity and a high negative predictive value in detecting synchronous malignant lesions located in the proximal colon distal to the obstructing left-sided colorectal cancer.

Conclusion · 2 of 2

As a result, patients underwent a single-stage surgery and were spared from an unnecessary second surgical intervention.

Accuracy of PET/CT for the Detection of Synchronous Malignant Lesions in Patients With Endoscopically Obstructive Colorectal Cancer.

Accuracy of PET/CT for the Detection of Synchronous Malignant Lesions in Patients With Endoscopically Obstructive Colorectal Cancer.

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